On the Antigenic Properties of Hemoglobin

Studies in Borreliae II. Some Immunologic, Biochemical and Physical Properties of the Antigenic Components of Borrelia turicatae

Immunogenetics of Human Haptoglobins

A B S T R A C T Using a radioimmunoassay method in conjunction with double diffusion studies, we characterized the antigenic determinants of the three Hp Bellevue phenotypes. An antigenic model based on these data indicates that each phenotype comprises a heterogeneous group of proteins with properties depending on their content of normal (hp,8) and of mutant (hp,8Bellevue) chains of haptoglobi...

Differences in antigenic specificity of human normal adult, fetal, and sickle cell anemia hemoglobin.

By MORRIS GOODMAN, PH.D.* AND DAN H. CAMPBELL, Pn.D. T HE DEMONSTRATION by Pauling et al.’ that sickle cell anemia hemoglobin has a slightly higher isoelectric point (0.2 pH unit) than normal human adult hemoglobin and the reports of differences in ability to form nematic liquid crystals2 and solubility differences in strong salt solutions3 suggest that differences might also exist in immunoche...

Differences in Antigenic Specificity of Human Normal Adult, Fetal, and Sickle Cell Anemia Hemoglobin

By MORRIS GOODMAN, PH.D.* AND DAN H. CAMPBELL, Pn.D. T HE DEMONSTRATION by Pauling et al.’ that sickle cell anemia hemoglobin has a slightly higher isoelectric point (0.2 pH unit) than normal human adult hemoglobin and the reports of differences in ability to form nematic liquid crystals2 and solubility differences in strong salt solutions3 suggest that differences might also exist in immunoche...

Expression and Antigenic Evaluation of VacA Antigenic Fragment of Helicobacter Pylori

Objective(s): Helicobacter pylori, a human specific gastric pathogen is a causative agent of chronic active gastritis. The vacuolating cytotoxin (VacA) is an effective virulence factor involved in gastric injury. The aim of this study was to construct a recombinant protein containing antigenic region of VacA gene and determine its antigenicity.   Materials and Methods: The antigenic region of V...